DHX8 Antilichaam - N-terminalgebied: HRP (ARP36380 P050-HRP)

DEAH (Asp-Glu-Ala-His) box polypeptide 8

DDX8, Dhr2, HRH1, PRP22, PRPF22

1659

Q14562

NP_004932

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the N terminal region of human DHX8

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is highly homologous to yeast Prp22. This protein facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome.

NUDCD1; UBC; LIN28A; XRN2; SRPK2; SRPK1; BAG3; PRPF38A; NKAP; ISY1; PRPF40A; ZCCHC10; RBMX2; SAP30BP; CHERP; RBM7; THOC1; MFAP1; DHX8; NOTCH1; KANSL1; PHF5A; MYPN; POLR1B; CRNKL1; TAF9; SMAD3; SMAD2; CAND1; CUL3; SIRT7; USP12

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

DHX8 is supported by BioGPS gene expression data to be expressed in HT1080

0.5 mg/ml

Cow: 100%; Dog: 88%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 93%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

139kDa

Wet Ice

1220

DHX8

DHX8

Rabbit

ATP-dependent RNA helicase DHX8

NM_004941

VKNGAEFTDSLISNLLRLIQTMRPPAKPSTSKDPVVKPKTEKEKLKELFP