DKFZp686M216 Antilichaam - N-terminalgebied : HRP (ARP33686_P050-HRP)

Aryl-hydrocarbon receptor nuclear translocator 2

WEDAS, bHLHe1

9915

Q9HBZ2

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

The immunogen is a synthetic peptide directed towards the N-terminal region of Human DKFZp686M216

This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting addition roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively.

TRIM42; CEP57L1; RFX6; MIPOL1; DYDC1; SSX2IP; DTX2; SYCE1; RIMBP3; ZNF341; LZTS2; USHBP1; CEP63; CCDC33; NPAS3; RINT1; NDE1; ADAMTSL4; MTUS2; IKZF3; RBCK1; SPAG5; TACC3; CALCOCO2; SORBS3; PDE4DIP; TRAF4; BZRAP1; TFIP11; SSBP3; DGCR6; NCOA3; TRIP6; TRAF2

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

79kDa

Wet Ice

This antibody is specific to both isoforms of hARNT2.

717

ARNT2

ARNT2

Rabbit

Putative uncharacterized protein DKFZp686M216 EMBL CAD97972.1

VTLPVAPMAATGQVRMAGAMPARGGKRRSGMDFDDEDGEGPSKFSRENHS