FAM134B Polyklonale Antilichaam, AbBy FluorTM 647 Vervoeging

Endoplasmic reticulum-anchored autophagy receptor that mediates ER delivery into lysosomes through sequestration into autophagosomes (PubMed:26040720) . Promotes membrane remodeling and ER scission via its membrane bending capacity and targets the fragments into autophagosomes via interaction with ATG8 family proteins (PubMed:26040720) . Required for long-term survival of nociceptive and autonomic ganglion neurons (PubMed:19838196, PubMed:26040720) .

JK1; JK-1; Reticulophagy receptor FAM134B; FAM134B

54463

Q9H6L5

Cytoplasm, Cell membrane

Human, Mouse, Rat

210-310/497

FAM134B

AbBy Fluor™ 647

KLH conjugated synthetic peptide derived from human FAM134B

WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)

Purified by Protein A.

650nm/665nm

1µg/µl

WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

There is a chance that this protein will cross-react with MSL2 based on a 73% non-sequential sequence similarity.

54463

Cow, Rabbit