Figla Antilichaam - C-terminaal gebied: Biotine (ARP37173_P050-Biotine)

Folliculogenesis specific basic helix-loop-helix

BHLHc, bHLHc8, FIGalpha

26910

O55208

NP_036143

Mouse, Rat

The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Figla

Figla is a germ-line specific transcription factor implicated in postnatal oocyte-specific gene expression. It plays a key regulatory role in the expression of multiple oocyte-specific genes, including those that initiate folliculogenesis and those that encode the zona pellucida (ZP1, ZP2 and ZP3) required for fertilization and early embryonic survival. It is essential for oocytes to survive and form primordial follicles. The persistence of FIGLA in adult females suggests that it may regulate additional pathways that are essential for normal ovarian development. Figla binds to the E-box (5'-CANNTG-3') of the ZPs (ZP1, ZP2, ZP3) promoters.

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Mouse: 100%; Rat: 86%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

21kDa

Wet Ice

194

FIGLA

Figla

Rabbit

Factor in the germline alpha

NM_012013

SSTRELLGNATQPTSCASGLKKEEEGPWAYAGHSEPLYSYHQSTVPETRS