FIP1L1 Antilichaam - C-terminal regio : HRP (ARP41031_P050-HRP)

FIP1 like 1 (S. cerevisiae)

Rhe, FIP1, hFip1

81608

Q6UN15

NP_112179

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the C terminal region of human FIP1L1

FIP1L1 is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly (A) polymerase and other factors to bring about cleavage and poly (A) addition. FIP1L1 contributes to poly (A) site recognition and stimulates poly (A) addition. It binds to U-rich RNA sequence elements surrounding the poly (A) site. FIP1L1 may act to tether poly (A) polymerase to the CPSF complex.

ZMYND19; CPSF4; NAA10; SGTA; GOLGA2; STAU1; UBC; WWOX; SUZ12; RNF2; EZH2; PRMT6; PRMT2; CLK2; HDAC9; CSNK2A1; LIG4; WDR33; CPSF2; CPSF3; CPSF1; NUP153; APP; COPS5; HNRNPA1; SRRM2; RNPS1

HRP: Horseradish Peroxidase

Polyclonal Antibody

IHC, WB

Affinity Purified

FIP1L1 is supported by BioGPS gene expression data to be expressed in Jurkat

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 86%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

65kDa

Zhao, X., (2005) J. Virol. 79 (7), 4270-4288

Wet Ice

594

FIP1L1

FIP1L1

Rabbit

Pre-mRNA 3'-end-processing factor FIP1

NM_030917

EYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGD