Fosfo-DDX3 (Thr322) Polyklonale Antilichaam, AbBy FluorTM 405 Vervoeging

DDX3 is involved in RNA metabolism. Two DDX3 paralogs are found in humans; DDX3X is encoded by a gene found on the X chromosome while DDX3Y is encoded by a gene on the Y chromosome. DDX3Y is exclusively expressed in testis and is required for normal spermatogenesis. DDX3X is ubiquitously expressed and predominantly localizes to the nuclear speckles, participating in RNA splicing, transcription, translation initiation, mRNA transport and cell cycle regulation. DDX3X also partakes in HIV-1 replication and hepatitis C viral infections.

P-DDX3 phospho T322; ATP dependent RNA helicase DDX3X; ATP-dependent RNA helicase DDX3X; CAP Rf; DBX; DDX14; DDX3X; DDX3X_HUMAN; DEAD Asp Glu Ala Asp box polypeptide 3 X linked; DEAD box; DEAD box protein 3; DEAD box protein 3 X-chromosomal; DEAD box X isoform; DEAD/H Asp Glu Ala Asp/His box polypeptide 3; DEAD/H box 3; Fibroblast Growth Factor Inducible 14; Fin14; Helicase like protein 2; Helicase-like protein 2; HLP2; X isoform; X-chromosomal.

1654

Thr322

Cytoplasm, Nucleus

Phospho-DDX3 (Thr322)

AbBy Fluor™ 405

KLH conjugated synthetic phosphopeptide derived from human DDX3 around the phosphorylation site of Thr322

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purified by Protein A.

401nm/421nm

1µg/µl

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Phosphorylation

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

1654

Human, Mouse, Rat, Dog, Cow, Sheep, Pig, Horse, Chicken