G22P1 Antilichaam - N-terminaal gebied: Biotine (ARP34117 T100-Biotine)

X-ray repair complementing defective repair in Chinese hamster cells 6

ML8, KU70, TLAA, CTC75, CTCBF, G22P1

2547

Q6FG89

NP_001460

Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the N terminal region of human G22P1

The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V (D) J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.

UBC; ELF3; EHF; CHD1L; SUMO2; SUMO3; MDM2; EMD; ATRX; RPA3; RPA2; RPA1; PCNA; EED; PRPF40A; SUPT5H; ST13; SET; PLOD2; PIN1; NARS; MSH2; RPSA; JUP; IMPDH1; MSH6; GART; DPYSL3; CTNNA1; SAMHD1; ATP6V1B2; GANAB; SWAP70; WBP4; HYOU1; FARSB; RANBP3; CUL2; CSDE1

Biotin

Polyclonal Antibody

IHC, WB

XRCC6 is supported by BioGPS gene expression data to be expressed in HepG2

0.5 mg/ml

Dog: 93%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Mouse: 93%; Rabbit: 86%; Rat: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

70kDa

Sawchuk, D.J., et al., (2004) J. Biol. Chem. 279 (28), 29821-29831

Wet Ice

609

XRCC6

XRCC6

Rabbit

X-ray repair cross-complementing protein 6

NM_001469

NFKNIYVLQELDNPGAKRILELDQFKGQQGQKRFQDMMGHGSDYSLSEVL