GTF2I Antilichaam - N-terminalgebied: HRP (ARP31910_T100-HRP)

General transcription factor IIi

WBS, DIWS, SPIN, IB291, BAP135, BTKAP1, TFII-I, WBSCR6, GTFII-I

2969

Q75M85

NP_001509

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the N terminal region of human GTF2I

GTF2I is a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23.This gene encodes a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. The exon (s) encoding 5' UTR has not been fully defined, but this gene is known to contain at least 34 exons, and its alternative splicing generates 4 transcript variants.

TP53; ZMYM3; PIAS2; TUBG1; TRAF6; SUMO2; SUMO3; AP2B1; DPY30; GCC1; MTUS2; MDM2; UBC; SUMO1; RPA3; RPA2; RPA1; EED; RNF2; SUZ12; CTPS2; WARS; RPL28; RAD23B; PRPS2; PRKDC; NUCB1; METTL1; ADSL; FBXO6; UBD; CBX2; TAB2; AP4S1; CBX4; MAPK12; C4BPA; MAP3K3; SLU

HRP: Horseradish Peroxidase

Polyclonal Antibody

IHC, WB

There is BioGPS gene expression data showing that GTF2I is expressed in HepG2

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

108kDa

Desgranges, Z.P., (2005) Mol. Cell. Biol. 25 (24), 10940-10952

Wet Ice

957

GTF2I

GTF2I

Rabbit

General transcription factor II-I

NM_001518

ILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVKEESEDPDYYQYNIQGSH