HMGB1 Antilichaam - N-terminalgebied: HRP (ARP38109 P050-HRP)

High mobility group box 1

HMG1, HMG3, HMG-1, SBP-1

3146

P09429

NP_002119

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the N terminal region of human HMGB1

HMGB1 belongs to the HMGB family. It contains 2 HMG box DNA-binding domains. The protein binds preferentially single-stranded DNA and unwinds double stranded DNA. The oxidized HMGB1 may accumulate even in cells under oxidative stress.

AGTRAP; HUWE1; UBC; ASB2; ASB1; ZNF24; MAPK1; HMGA1; ITGA4; FN1; HNF1A; SSRP1; SMARCE1; PSEN1; XPC; XPA; RAD23B; CDK2; TFAP4; TERF2IP; TERF2; HHV8GK18_gp81; SUMO2; FCP1; DNM2; HSPA8; HMGB2; PDIA3; Ccdc15; POU5F1; H3F3A; CREBBP; CDK1; TBP; LRIF1; RASSF4; N

HRP: Horseradish Peroxidase

Polyclonal Antibody

Affinity Purified

HMGB1 is strongly supported by BioGPS gene expression data to be expressed in HeLa

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

25kDa

Straino, S., (2008) J. Invest. Dermatol. 128 (6), 1545-1553

Wet Ice

215

HMGB1

HMGB1

Rabbit

High mobility group protein B1

NM_002128

GKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKT