HNRNPA2B1 Antilichaam - N-terminaal gebied: Biotine (ARP41035_P050-Biotine)

Heterogeneous nuclear ribonucleoprotein A2/B1

RNPA2, HNRPA2, HNRPB1, SNRPB1, HNRNPA2, HNRNPB1, IBMPFD2, HNRPA2B1

3181

P22626

NP_112533

Human, Mouse, Rat, Dog, Horse, Pig, Rabbit, Yeast

The immunogen is a synthetic peptide directed towards the N terminal region of human HNRNPA2B1

HNRNPA2B1 belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs) . The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA) . These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. HNRNPA2B1 has two repeats of quasi-RRM domains that bind to RNAs.This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs) . The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA) . These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. This gene has been described to generate two alternatively spliced transcript variants which encode different isoforms.

PA2G4; HUWE1; UBC; TP53; AURKA; SUMO2; SUMO3; CDKN1A; NEDD1; HAUS1; CEP57; STAU1; SUMO1; NEDD8; MDM2; ERG; ASB2; RPA3; RPA2; RPA1; HNRNPL; EED; VHL; rev; RPL39; RPL27A; RAD51; QARS; PTBP1; PSMD13; PSMB4; PSMB1; PSMA6; PSMA5; PSMA4; PAFAH1B2; YBX1; MRE11A

Biotin

Polyclonal Antibody

IHC, WB

Affinity Purified

HNRNPA2B1 is supported by BioGPS gene expression data to be expressed in Jurkat

0.5 mg/ml

Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Yeast: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

37kDa

Goina, E., (2008) Mol. Cell. Biol. 28 (11), 3850-3860

Wet Ice

353

HNRNPA2B1

HNRNPA2B1

Rabbit

Heterogeneous nuclear ribonucleoproteins A2/B1

NM_031243

MEKTLETVPLERKKREKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDC