IL-1 eiwit (mens)

IL-1

IL1F, IL-1F, pro IL1F, IL-1, IL1-BETA, IL1F2, IL1 beta, IL1B, catabolin, IL-1B, pro Catabolin, pro IL1B, pro IL1F2, pro leukocytic endogenous mediator, pro leukocytic pyrogen, pro lymphocyte activating factor, pro mononuclear cell factor, IL-1F2, IL 1B, IL-1 beta

P01584

Cell culture, ELISA

> 95 % as determined by reducing SDS-PAGE.

1. Immobilized recombinant human IL1B at 2 μg/mL (100μl/well) can bind recombinant human IL1R2 with a linear range of 6. 25-400 ng/ml. 2. Measured in a cell proliferation assay using D10.G4. 1 mouse helper T cells. The ED50 for this effect is typically 2-8 pg/mL. 3. Immobilized human IL1B at 10 μg/mL (100 μl/well) can bind human IL1R1, The EC50 of human IL1R1 is 0.48 μg/mL. 4. Measured by its ability to induce Interferon gamma secretion by human natural killer lymphoma NK-92 cells. The ED50 for this effect is 0.4-2 ng/mL.

Ala 117-Ser 269

17 kDa

Human