Integrine alfa V beta 8 Proteïne, humaan, recombinant (His)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
0.971
Integrin alpha V beta 8 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligands. ITGAVB8 does not appear to assume different activation states; and the cytoplasmic tail does not connect to the cytoskeleton. It binds ligands containing an RGD motif; including vitronectin; fibrin and the latency associated peptide (LAP) of the latent TGF-beta complex. High affinity binding of alpha V beta 8 to LAP allows proteolytic cleavage by MT1-MMP; which releases active TGF-beta. This mechanism differs from that of alpha V beta 6; the other alpha V integrin which can activate TGF-beta from latency through non-proteolytic mechanisms.
Ice Packs
-20°C
Beschrijving
Integrine alfa V beta 8 Proteïne, humaan, recombinant (His) Beschikbaar in 5 µg. Bestel eenvoudig online met snelle levering.
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