ITPK1 Antilichaam - N-terminalgebied: HRP (ARP54993 P050-HRP)

Inositol-tetrakisphosphate 1-kinase

ITRPK1

3705

Q13572

NP_055031

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the N terminal region of human ITPK1

ITPK1 is the kinase that can phosphorylate various inositol polyphosphate such as Ins (3,4,5,6) P4 or Ins (1,3,4) P3. It may also act as an isomerase that interconverts the inositol tetraphosphate isomers Ins (1,3,4,5) P4 and Ins (1,3,4,6) P4 in the presence of ADP and magnesium. It probably acts as the rate-limiting enzyme of the InsP6 pathway. ITPK1 modifies TNF-alpha-induced apoptosis by interfering with the activation of TNFRSF1A-associated death domain.

UBC; TP53; NFKBIA; JUN; ITPK1; GPS1; COPS8; TRAF2

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

45kDa

Chamberlain, P.P., (2007) J. Biol. Chem. 282 (38), 28117-28125

Wet Ice

414

ITPK1

ITPK1

Rabbit

Inositol-tetrakisphosphate 1-kinase

NM_014216

MEVVQLNLSRPIEEQGPLDVIIHKLTDVILEADQNDSQSLELVHRFQEYI