KCNN4 (NM 002250) Humaan Recombinant eiwit

The protein encoded by this gene is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. The encoded protein may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily. [provided by RefSeq, Jul 2008]

Purified recombinant protein of Human potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 (KCNN4), Phe301-Lys360, with N-terminal His-ABP tag, expressed in E. coli, 50ug

DHS2; hIKCa1; hKCa4; hSK4; IK; IK1; IKCA1; KCa3.1; KCA4; SK4

3783

O15554

NM_002250

19q13.31

E. coli

N-His-ABP

>50 ug/mL as determined by microplate BCA method

> 80% as determined by SDS-PAGE and Coomassie blue staining

Liquid

50mM Tris, 8M Urea, pH8.0.

Druggable Genome, Ion Channels: Potassium, Transmembrane

22.4 kDa

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

KCNN4

Human

NP_002241

https://www.ncbi.nlm.nih.gov/gene/3783

https://www.uniprot.org/uniprot/O15554

https://www.ncbi.nlm.nih.gov/nuccore/NM_002250

https://www.ncbi.nlm.nih.gov/nuccore/NP_002241