KLF4 Antilichaam - N-terminalgebied: HRP (ARP35721_T100-HRP)

Kruppel-like factor 4 (gut)

EZF, GKLF

9314

O43474

NP_004226

Human, Cow, Dog, Horse, Pig, Rabbit, Sheep

The immunogen is a synthetic peptide directed towards the N terminal region of human KLF4

The mammalian Kruppel-like transcription factor, KLF4 is involved in preventing centrosome amplification following DNA damage caused by gamma-irradiation. It is both necessary and sufficient in preventing centrosome amplification following gamma-radiation-induced DNA damage and does so by transcriptionally suppressing cyclin E expression n. Kruppel-like factor 4 is also known to exhibit checkpoint function during the G1/S and G2/M transitions of the cell cycle.

EP300; CREBBP; SETD7; CTBP1; Dlg4; APP; CUL2; VHL; UBC; TCEB2; SP1; RELA; PRKCD; PPARG; SMARCA4; HDAC2; HDAC7; KAT5; HDAC1; HDAC5; ELK1; KLF6; TP53

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

0.5 mg/ml

Cow: 80%; Dog: 87%; Horse: 87%; Human: 100%; Pig: 80%; Rabbit: 85%; Sheep: 80%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

50kDa

Yoon, H.S., (2005) Oncogene 24 (25), 4017-4025

Wet Ice

470

KLF4

KLF4

Rabbit

Krueppel-like factor 4

NM_004235

GAACGGSNLAPLPRRETEEFNDLLDLDFILSNSLTHPPESVAATVSSSAS