KPNA1 Antilichaam - N-terminalgebied: HRP (ARP54670_P050-HRP)

Karyopherin alpha 1 (importin alpha 5)

RCH2, SRP1, IPOA5, NPI-1

3836

P52294

NP_002255

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the N terminal region of human KPNA1

Recombination activating proteins RAG1 and RAG2 regulate and mediate V (D) J recombination, the process by which genes for immunoglobulins and T-cell receptors are generated. Several other ubiquitously expressed proteins are thought to be recruited in the recombination process. Among these are the genes affected in severe combined immune deficiency and genes involved in ds-DNA break repair. KPNA1 interacts with RAG1 and may play a role in V (D) J recombination.Recombination activating proteins RAG1 and RAG2 regulate and mediate V (D) J recombination, the process by which genes for immunoglobulins and T-cell receptors are generated. Several other ubiquitously expressed proteins are thought to be recruited in the recombination process. Among these are the genes affected in severe combined immune deficiency and genes involved in ds-DNA break repair. The protein encoded by this gene interacts with RAG1 and may play a role in V (D) J recombination. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

UBC; TAF9; CLK4; NUP50; ANP32B; XRN2; rev; TRMT61A; KCTD12; NPM1; GABPA; DCAF6; LIMCH1; HECW2; CLK3; HDAC2; HDAC1; GOPC; HDAC6; CRADD; LMO4; BCAR3; FOSL1; SKP2; ORC4; IL1RAP; AICDA; TP53BP1; KPNB1; RAG1; NOSIP; DCAF8; ANP32A; CAND1; COPS5; CUL1; CUL3; CUL

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

KPNA1 is strongly supported by BioGPS gene expression data to be expressed in 721_B

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

60kDa

Theodore, M., (2008) J. Biol. Chem. 283 (14), 8984-8994

Wet Ice

538

KPNA1

KPNA1

Rabbit

Importin subunit alpha-1

NM_002264

TTPGKENFRLKSYKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVA

Alpha-1