L3MBTL Antilichaam - N-terminalgebied: FITC (ARP35895 P050-FITC)

L (3) mbt-like 1 (Drosophila)

L3MBTL, ZC2HC3, H-L (3) MBT, dJ138B7.3

26013

Q9Y468

NP_056293

Human, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the N terminal region of human L3MBTL

L3MBTL is the homolog of a protein identified in Drosophila as a suppressor of malignant transformation of neuroblasts and ganglion-mother cells in the optic centers of the brain. L3MBTL is localized to condensed chromosomes in mitotic cells. Overexpression of this gene in a glioma cell line results in improper nuclear segregation and cytokinesis producing multinucleated cells.This gene encodes the homolog of a protein identified in Drosophila as a suppressor of malignant transformation of neuroblasts and ganglion-mother cells in the optic centers of the brain. This gene product is localized to condensed chromosomes in mitotic cells. Overexpression of this gene in a glioma cell line results in improper nuclear segregation and cytokinesis producing multinucleated cells. Alternatively spliced transcript variants encoding different isoforms have been identified.

VCP; UBC; PCNA; MCM7; MCM6; MCM5; MCM4; MCM3; CDC45; MCM2; SETD8; TP53; HIST1H1E; L3MBTL1; ETV7; ETV6; HIST2H4A; CBX3; RB1; HIST1H1B; SETD7; CBX5

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

There is BioGPS gene expression data showing that L3MBTL1 is expressed in HEK293T

0.5 mg/ml

Cow: 86%; Dog: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Rabbit: 79%; Rat: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

86kDa

Min, J., (2007) Nat. Struct. Mol. Biol. 14 (12), 1229-1230

Wet Ice

772

L3MBTL1

L3MBTL1

Rabbit

Lethal (3) malignant brain tumor-like protein 1

NM_015478

LLKPMKKRKRREYQSPSEEESEPEAMEKQEEGKDPEGQPTASTPESEEWS