LGALS3 Antilichaam - N-terminalgebied: HRP (ARP54688_P050-HRP)

Galectin 3

L31, GAL3, MAC2, CBP35, GALBP, GALIG, LGALS2

3958

P17931

NP_002297

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

The immunogen is a synthetic peptide directed towards the N terminal region of human LGALS3

This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.

PRR13; SS18L1; PPIG; LGALS3; GOLGA2; MAP1LC3A; SQSTM1; RAB7A; LAMP1; EGFR; CFTR; PAXIP1; BARD1; AGPS; IGBP1; GTF2I; CLNS1A; APP; SLC25A5; ACTA1; MYOC; LGALS3BP; CYHR1; GEMIN4; SUFU; CUBN; CSNK1A1; LIM2; FCGR2A; ELN; MMP2; CSNK2A2; CSNK2A1; C1GALT1C1; LGAL

HRP: Horseradish Peroxidase

Polyclonal Antibody

IHC, WB

Affinity Purified

LGALS3 is supported by BioGPS gene expression data to be expressed in MCF7

0.5 mg/ml

Cow: 93%; Dog: 93%; Guinea Pig: 92%; Horse: 92%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 92%; Rat: 93%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

26kDa

Bartolazzi, A., (2008) Lancet Oncol. 9 (6), 543-549

Wet Ice

250

LGALS3

LGALS3

Rabbit

Galectin-3

NM_002306

GASYPGAYPGQAPPGAYPGQAPPGAYPGAPGAYPGAPAPGVYPGPPSGPG