MAART1 Antilichaam - N-terminalgebied: FITC (ARP43239 P050-FITC)

Membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase

MARCH1, RNF171, MARCH-I

55016

Q8TCQ1-2

NP_060393

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the N terminal region of human MARCH1

MARCH1 is an E3 ubiquitin-protein ligase that may mediate ubiquitination of TFRC, CD86 and FAS, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.

TNFRSF10A; UBE2H; UBE2D1; CDC34; TFRC; UBC; HLA-DRB1; HLA-DRA; PPP2R1B; PPP2R1A; CD86

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

31kDa

De (2008) Proc. Natl. Acad. Sci. U.S.A. 105 (9), 3491-3496

Wet Ice

272

44986

MARCH1

Rabbit

E3 ubiquitin-protein ligase MARCH1

NM_017923

LQASSPTTGTAPRSQSRLSVCPSTQDICRICHCEGDEESPLITPCRCTGT