MAART11 Antilichaam - C-terminalgebied: FITC (ARP43511-P050-FITC)

Membrane associated ring-CH-type finger 11

RNF226, MARCH11, MARCH-XI

441061

A6NNE9

NP_001096032

Human

The immunogen is a synthetic peptide directed towards the C-terminal region of Human MARHB

MARCH11 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19) . These enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their intracellular transport. March11 appears to have a role in ubiquitin-mediated protein sorting in the trans-Golgi network (TGN) -multivesicular body (MVB) transport pathway (Morokuma et al., 2007 [PubMed 17604280]) .[supplied by OMIM, Apr 2010]

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

44kDa

Wet Ice

402

44996

MARCH11

Rabbit

E3 ubiquitin-protein ligase MARCH11

RVFKRWRAVNLHWDVLNYDKATDIEESSRGESSTSRTLWLPLTALRNRNL