MMP9 Antilichaam - N-terminaal gebied: Biotine (ARP3090_T100-Biotine)

Matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)

GELB, CLG4B, MMP-9, MANDP2

4318

P14780

NP_004985

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

The immunogen is a synthetic peptide directed towards the N terminal region of human MMP9

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by MMP9 degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.

CXCL5; PZP; MMP26; RECK; KISS1; PRSS2; EPHB2; BTC; LCN2; COL4A6; COL4A5; TIMP3; THBS2; THBS1; MMP10; MMP7; PLG; CXCL1; TFPI; CXCL8; FN1; MMP9; COL1A2; COL1A1; COL4A4; COL4A1; COL4A2; COL4A3; HAPLN1; CD44; AREG; TGFB1; CXCL6

Biotin

Polyclonal Antibody

IHC, WB

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

78kDa

Nozell, S., et al., (2004) J. Biol. Chem. 279 (37), 38577-38589

Wet Ice

707

MMP9

MMP9

Rabbit

Matrix metalloproteinase-9

NM_004994

VAEHGDGYPFDGKDGLLAHAFPPGPGIQGDAHFDDDELWSLGKGVVVPTR