MNT Antilichaam - N-terminalgebied : HRP (ARP39412_P050-HRP)

MAX binding protein

ROX, MAD6, MXD6, bHLHd3, lncRNA-HAL

4335

Q99583

NP_064706

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Yeast

The immunogen is a synthetic peptide directed towards the N terminal region of human MNT

The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. MNT is a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain.The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Dlg4; ELAVL1; CEBPA; MAX; MAD1L1; MYC; HDAC1; SIN3A; MNT; MLX; HMGB1

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

MNT is supported by BioGPS gene expression data to be expressed in HepG2

0.5 mg/ml

Cow: 93%; Dog: 93%; Horse: 80%; Human: 100%; Mouse: 93%; Pig: 80%; Rabbit: 93%; Rat: 93%; Yeast: 92%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

62kDa

Montagne, M., (2008) J. Mol. Biol. 376 (1), 141-152

Wet Ice

582

MNT

MNT

Rabbit

Max-binding protein MNT

NM_020310

SIETLLEAARFLEWQAQQQQRAREEQERLRLEQEREQEQKKANSLARLAH