MRPS18B Antilichaam - N-terminalgebied: HRP (ARP62873 P050-HRP)

Mitochondrial ribosomal protein S18B

PTD017, S18amt, C6orf14, HSPC183, MRPS18-2, HumanS18a, MRP-S18-2

28973

Q9Y676

NP_054765

Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Zebrafish

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins.

TUBGCP4; CEP250; TUBGCP3; VCP; TP53; NEDD1; UBC; PARK2; EXOSC6; EWSR1; mug82; ICT1; EBNA3B; RB1; MRPS9; MRPS26; MRPS25; MRPS35; MRPS22; UBR5; MRPS28; QARS; MYH9; KARS; HNRNPAB; FUS; CAND1; CUL3; Ybx1; NFKBIL1

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 79%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Mouse: 79%; Rabbit: 86%; Rat: 86%; Zebrafish: 83%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

28kDa

Wet Ice

258

MRPS18B

MRPS18B

Rabbit

28S ribosomal protein S18b, mitochondrial

NM_014046

SVPISPYKDEPWKYLESEEYQERYGSRPVWADYRRNHKGGVPPQRTRKTC