MYST2 Antilichaam - N-terminalgebied: Biotine (ARP31518 P050-Biotine)

K (lysine) acetyltransferase 7

HBO1, HBOA, MYST2, ZC2HC7

11143

O95251

NP_008998

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the N terminal region of human MYST2

MYST2 belongs to the MYST family, which is characterized by a highly conserved C2HC zinc finger and a putative histone acetyltransferase domain. MYST2 specifically represses AR-mediated transcription. MYST2 is a new AR-interacting protein capable of modulating AR activity. It could play a significant role in regulating AR-dependent genes in normal and prostate cancer cells. The biochemical and genetic interactions of MYST family protein MYST2 with two components of the replication apparatus, MCM2 and ORC1, suggest that MYST2-associated HAT activity may play a direct role in the process of DNA replication. MYST2 is a positive regulatory factor for prereplicative complex assembly.

UBC; RNF2; EZH2; VIM; CDK11B; APP; HAP1; BARD1; LRIF1; ING4; JADE1; CSNK1E; DYNC1I1; CDT1; tat; HIST1H4A; HIST1H3A; HIST2H2AC; GMNN; ORC2; MCM2; CDC6; JUN; KIAA1377; CEP70; CBX8; CAAP1; KCTD13; PPID; WDR33; NINL; ZBTB8B; HOOK2; KATNBL1; POLB; CALCOCO2; AT

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

71kDa

Wu, Z.Q. (2008) Proc. Natl. Acad. Sci. U.S.A. 105 (6), 1919-1924

Wet Ice

611

KAT7

KAT7

Rabbit

Histone acetyltransferase KAT7

NM_007067

MPRRKRNAGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLS