NCIR1 Antilichaam - N-terminalgebied: FITC (ARP32479 P050-FITC)

Nuclear receptor corepressor 1

N-CoR, TRAC1, N-CoR1, hN-CoR, PPP1R109

9611

Q60974

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Yeast

The immunogen is a synthetic peptide directed towards the N terminal region of human NCOR1

NCOR1 mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p.

RARA; TP53; ESR1; PHB2; ZBTB16; THRB; THRA; CREB1; JUN; PPARG; SQSTM1; HDAC3; UBE2I; SOX2; HDAC7; HDAC5; HDAC4; UBC; SKIL; SKI; AR; SMAD4; CSNK2A1; RUNX1T1; CXADR; TBL1XR1; vif; C1D; CHUK; YWHAZ; SMARCE1; SMARCD1; SMARCA2; RBBP4; BPTF; HMGXB4; TAB2; NCOR2

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

IHC, WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 92%; Horse: 92%; Human: 100%; Mouse: 100%; Rat: 92%; Yeast: 85%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

270kDa

Horlein, A.J., et al., (1995) Nature 377 (6548), 397-404

Wet Ice

2453

NCOR1

NCOR1

Rabbit

Nuclear receptor corepressor 1

NENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEEDKAEKTEKKEEEKK