NFATC1 Antilichaam - C-terminalgebied: HRP (ARP39978_P050-HRP)

Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1

NFAT2, NFATc, NF-ATC, NF-ATc1.2

4772

B5B2M5

NP_765975

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish

The immunogen is a synthetic peptide directed towards the C terminal region of human NFATC1

NFATC1 is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Different isoforms of this protein may regulate inducible expression of different cytokine genes.

YWHAQ; OGT; PML; GZF1; FOXP3; HDAC4; PIAS1; SUMO1; UBE2I; RPS6KB1; RPS6KA3; HDAC2; HDAC1; HNRNPA1; TUBA1A; KPNB1; HDAC5; KAT2B; EP300; PARP1; HDAC3; PPP3R1; MAPK14; GNB2L1; PRKCA; SPI1; PIM1; EGR2; EGR1

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB, IHC

Affinity Purified

0.5 mg/ml

Cow: 79%; Dog: 93%; Guinea Pig: 91%; Horse: 91%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 86%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

100kDa

Wet Ice

930

NFATC1

NFATC1

Rabbit

Nuclear factor of activated T-cells c1 isoform IB-IXL EMBL ACG55580.1

NM_172387

LLPEVHEDGSPNLAPIPVTVKREPEELDQLYLDDVNEIIRNDLSSTSTHS