NR1H4 Antilichaam - middengebied: HRP (ARP45626-P050-HRP)

Nuclear receptor subfamily 1, group H, member 4

BAR, FXR, HRR1, HRR-1, PFIC5, RIP14

9971

B6ZGS9

NP_005114

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

The immunogen is a synthetic peptide directed towards the middle region of human NR1H4

NR1H4 is the receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. NR1H4 represses the transcription of the cholesterol 7-alpha-hydroxylase gene (CYP7A1) through the induction of NR0B2 or FGF19 expression, via two d

SMARCD3; HDAC6; SUMO1; NCOR2; ESR1; RRM2; GPS2; RXRG; GAPDH; RXRA; EP300; SIRT1; SRC; NCOA6; CARM1; HIST1H4A; HIST1H3A; PRMT1; NCOR1; XRCC5; PRKDC; XRCC6; NCOA1; CASP8; SMARCD1

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 93%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 93%; Rat: 93%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

54kDa

Kaeding, J., (2008) Biochem. J. 410 (2), 245-253

Wet Ice

472

NR1H4

NR1H4

Rabbit

Farnesoid X receptor EMBL BAH02290.1

NM_005123

SAVEAMFLRSAEIFNKKLPSGHSDLLEERIRNSGISDEYITPMFSFYKSI