NR1I3 Antilichaam - N-terminalgebied: FITC (ARP45623_T100-FITC)

Nuclear receptor subfamily 1, group I, member 3

CAR, CAR1, MB67

9970

Q5VTW5

NP_005113

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Pig

The immunogen is a synthetic peptide directed towards the N terminal region of human NR1I3

NR1I3 mediates the induction of transcription of cytochrome P450 (CYP) genes by phenobarbital (PB) and PB-type inducers. NR1I3 activation induces hepatic expression of detoxification enzymes and transporters and increases liver size. NR1I3 can also regulate both liver homeostasis and tumorigenesis in response to xenobiotic stresses.

HSP90AA1; RXRA; CHD9; SNX13; SNRPD3; IGH; PSMC5; PSMC4; EIF3I; SRC; MAP4; FTH1; HNF4A; NR0B2; PPARGC1A; MED1; NCOA1; POU1F1

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

IHC, WB

0.5 mg/ml

Cow: 90%; Dog: 92%; Guinea Pig: 79%; Human: 100%; Mouse: 92%; Pig: 100%; Rat: 92%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

39kDa

Ferguson, S.S., (2005) Mol. Pharmacol. 68 (3), 747-757

Wet Ice

348

NR1I3

NR1I3

Rabbit

Nuclear receptor subfamily 1 group I member 3

NM_005122

MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFA