NSC 104999
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
NSC 104999 is a Grb7 SH2 domain binder with moderate affinity (Kd = 32.3 μM) . NSC 104999 exhibits anticancer activity against breast cancer[1].
1118745-14-4
12352005
EGFR
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Cancer
O=C(C1=CC=C(C(NC2=CC(C3=NCCN3)=CC(C(NCCCC)=O)=C2)=O)C=C1)NC4=CC(C5=NCCN5)=CC(C(NCCCC)=O)=C4
C36H42N8O4
650.77
[1]Ambaye ND, et al. The discovery of phenylbenzamide derivatives as Grb7-based antitumor agents. ChemMedChem. 2013 Feb;8 (2) :280-8.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-180480/
Reference compound1
No Development Reported
Beschrijving
NSC 104999 is a Grb7 SH2 domain binder with moderate affinity (Kd = 32.3 μM) . NSC 104999 exhibits anticancer activity against breast cancer[1].
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