ORC3L Antilichaam - N-terminaal gebied: HRP (ARP62224 P050-HRP)

Origin recognition complex, subunit 3

LAT, ORC3L, LATHEO

23595

Q9UBD5-2

NP_862820

Human, Mouse, Rat, Cow, Dog, Pig, Rabbit, Yeast, Zebrafish

The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Studies of a similar gene in Drosophila suggested a possible role of this protein in neuronal proliferation and olfactory memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene.

ORC5; ORC4; ORC1; MCM7; CDC6; MCM10; ORC6; CCNE2; CDC45; LRWD1; ORC2; APP; SUMO2; XRCC5; UBC; XRCC6; ZBP1; DBF4; ORC3; MCM5; CDK4; TERF2; BRCA1; MCM4

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

ORC3 is supported by BioGPS gene expression data to be expressed in HepG2

0.5 mg/ml

Cow: 93%; Dog: 93%; Human: 100%; Mouse: 79%; Pig: 90%; Rabbit: 93%; Rat: 83%; Yeast: 90%; Zebrafish: 85%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

82kDa

Wet Ice

712

ORC3

ORC3

Rabbit

Origin recognition complex subunit 3

NM_181837

RFETYQLIWQQMKSENERLQEELNKNLFDNLIEFLQKSHSGFQKNSRDLG

3