PAXIP1 Antilichaam - N-terminalgebied: FITC (ARP51642_P050-FITC)

PAX interacting (with transcription-activation domain) protein 1

PTIP, TNRC2, CAGF28, CAGF29, PACIP1, PAXIP1L

22976

Q6ZW49

EAX04525

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the N terminal region of human PAXIP1

PAXIP1 functions as a key component of the DNA damage response, and phosphoserine or phosphothreonine-specific binding modules. PAXIP1 recognizes substrates phosphorylated by the kinases ataxia telangiectasia-mutated (ATM), ataxia telangiectasia and RAD3-related (ATR) in response to gamma irradiation. It may play a role in PAX2-dependent transcriptional regulation. PAXIP1 plays a role in early development, most probably in cell proliferation.

MAPRE2; POM121; NXT1; PPARG; XAGE1E; SMAD2; SPATA18; COMTD1; BTBD16; DIS3L; LACTB; HNRNPLL; ZNF251; ZNF622; BTBD6; C7orf50; FAM175A; TMEM120A; FAHD1; TM2D3; ATHL1; CENPU; DYNC2H1; BRCC3; KRI1; ANAPC1; NOM1; POLR1E; NCAPG; AASDHPPT; RBM25; CATSPERG; WDR48

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

PAXIP1 is supported by BioGPS gene expression data to be expressed in 721_B

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

74kDa

Wet Ice

697

PAXIP1

PAXIP1

Rabbit

PAX-interacting protein 1

NM_007349

MFDDSSDSSPEKQERNLNWTPAEVPQLAAAKRRLPQGKEPGLINLCANVP