PCDHA11 Antilichaam - N-terminalgebied: HRP (ARP49346_P050-HRP)

Protocadherin alpha 11

CNR7, CNRN7, CNRS7, CRNR7, PCDH-ALPHA11

56138

Q9Y5I1-2

NP_114067

Human, Mouse, Rat, Cow, Guinea Pig, Horse, Pig, Rabbit

This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

UBC

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 93%; Guinea Pig: 77%; Horse: 92%; Human: 100%; Mouse: 93%; Pig: 85%; Rabbit: 86%; Rat: 91%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

85kDa

Wet Ice

810

PCDHA11

PCDHA11

Rabbit

Protocadherin alpha-11

NM_031861

RLSKNEYFSLDSPTNGKQIKRLSLILKKSLDREKTPELNLLLTATDGGKP