PNKP Antilichaam - N-terminaal gebied: Biotine (ARP52311 P050-Biotine)

Polynucleotide kinase 3'-phosphatase

PNK, AOA4, MCSZ, CMT2B2, EIEE10

11284

Q96T60

NP_009185

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse

The immunogen is a synthetic peptide directed towards the N terminal region of human PNKP

This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.

ZNF639; IKZF1; TNIP1; ZBTB14; RPA3; RPA2; RPA1; EED; rev; KDM1A; SUV39H1; HNRNPU; GZMK; XRCC6; CDK11B; PARP1; MCM3; SMAD5; LIG4; XRCC1; TCOF1; SSRP1; PRKDC; NRD1; NASP; MCM5; C18orf25; UBE2O; GEMIN4; AGTPBP1; PNKP; SUPT16H; VPRBP; NOLC1; TRIM26; XRCC5; XR

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

57kDa

Wet Ice

521

PNKP

PNKP

Rabbit

Bifunctional polynucleotide phosphatase/kinase

NM_007254

MGEVEAPGRLWLESPPGGAPPIFLPSDGQALVLGRGPLTQVTDRKCSRTQ