POLR2I Antilichaam - N-terminalgebied: HRP (ARP35790 P050-HRP)

Polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa

RPB9, hRPB14.5

5438

P36954

NP_006224

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

The immunogen is a synthetic peptide directed towards the N terminal region of human POLR2I

POLR2I is a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with two other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. POLR2I has two zinc finger motifs with conserved cysteines and the subunit does possess zinc binding activity. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with two other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. The product of this gene has two zinc finger motifs with conserved cysteines and the subunit does possess zinc binding activity. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

ESR1; TCEB3; SRC; PSMB9; UBC; MED19; MED26; RECQL5; TBCD; BRCA1; CPSF6; POLR2E; POLR2D; POLR2C; POLR2B; POLR2A; DCUN1D1; CUL5; MYC; tat; WDR48; POLR2H; MED10; MED29

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

POLR2I is supported by BioGPS gene expression data to be expressed in HepG2

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 83%; Zebrafish: 93%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

14kDa

Grimwood, J., (2004) Nature 428 (6982), 529-535

Wet Ice

125

POLR2I

POLR2I

Rabbit

DNA-directed RNA polymerase II subunit RPB9

NM_006233

ACRNCDYQQEADNSCIYVNKITHEVDELTQIIADVSQDPTLPRTEDHPCQ

RPB9