PPP1R8 Antilichaam - N-terminalgebied: HRP (ARP40753_T100-HRP)

Protein phosphatase 1, regulatory subunit 8

ARD1, ARD-1, NIPP1, NIPP-1, PRO2047

5511

Q12972

NP_054829

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the N terminal region of human PPP1R8

This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.

APPBP2; UBC; FBXO25; HMGA1; WDR77; CTNNBL1; PPIL1; PPP1CC; PPP1CA; NF2; APP; SF3A2; Cep72; PPP1CB; SUZ12; RBBP4; EZH2; EED; RBM48; SF3B1; SETDB1; MELK; HDAC2; C14orf1; STC2; CDC5L; CRMP1; PRKACA; GBP2; LYN; CSNK2A2; CSNK2A1; NME2

HRP: Horseradish Peroxidase

Polyclonal Antibody

IHC, WB

PPP1R8 is supported by BioGPS gene expression data to be expressed in HepG2

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

39kDa

Lesage, B., (2004) J. Biol. Chem. 279 (53), 55978-55984

Wet Ice

351

PPP1R8

PPP1R8

Rabbit

Nuclear inhibitor of protein phosphatase 1

NM_014110

THGTFLGHIRLEPHKPQQIPIDSTVSFGASTRAYTLREKPQTLPSAVKGD