PTGDS Antilichaam - N-terminaal gebied: Biotine (ARP48154_P050-Biotine)

Prostaglandin D2 synthase 21kDa (brain)

PDS, PGD2, PGDS, LPGDS, PGDS2, L-PGDS

5730

P41222

NP_000945

Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the N terminal region of human PTGDS

PTGDS is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2) . PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation.The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2) . PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

PTGDR; HSP90AA1; KRTAP10-3; KRTAP10-7; Hk3; Hk2; ARRB2; ARR3; RARRES3; CAPN1; PTGDS; MLH1; BCAT2; ATXN1; SHBG; CACNA1A; EGFR; PTGFR; PTGER2; PTGER1

Biotin

Polyclonal Antibody

IHC, WB

Affinity Purified

0.5 mg/ml

Dog: 86%; Guinea Pig: 79%; Horse: 79%; Human: 100%; Mouse: 100%; Rabbit: 80%; Rat: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

21kDa

Lovell, M.A., (2008) Neurology 70 (23), 2212-2218

Wet Ice

190

PTGDS

PTGDS

Rabbit

Prostaglandin-H2 D-isomerase

NM_000954

MATHHTLWMGLALLGVLGDLQAAPEAQVSVQPNFQQDKFLGRWFSAGLAS