PTPA-antilichaam - N-terminaal gebied: Biotine (ARP62067 P050-Biotine)

Protein phosphatase 2 phosphatase activator

PP2A, PR53, PPP2R4

5524

Q15257

NP_821068

Human

Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.

AMOT; MID1; BHLHB9; SP3; STAT1; IER3; UBC; PRKCB; MAPT; EIF4EBP1; RACGAP1; APP; CAV1; AKT1; MAP2K3; MARK2; ATM; STK26; AURKB; CYLD; PPP1CA; HHV8GK18_gp81; SP1; PPP2CA; MDM2; SET; ARRB2; PIM1; PTEN; PPP2R1A; MYOCD; MYLPF; CCT5; CCT8; CCT2; CCT4; CCT7; CCT3

Biotin

Polyclonal Antibody

WB

Affinity Purified

PPP2R4 is strongly supported by BioGPS gene expression data to be expressed in MDA-MB435

0.5 mg/ml

Human: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

39kDa

Wet Ice

358

PTPA

PTPA

Rabbit

Serine/threonine-protein phosphatase 2A activator

NM_178001

WKRSQAYADYIGFILTLNEGVKGKKLTFEYRVSEMWNEVHEEKEQAAKQS