PYDC1 Antilichaam - N-terminaal gebied : HRP (ARP55560 P050-HRP)

PYD (pyrin domain) containing 1

ASC2, POP1, PYC1, cPOP1

260434

Q8WXC3

NP_690865

Human, Cow, Dog, Goat, Guinea Pig, Horse, Yeast

The immunogen is a synthetic peptide directed towards the N-terminal region of Human PYDC1

PYDC1 associates with apoptosis-associated specklike protein containing a CARD domain (ASC) and modulates its ability to collaborate with pyrin and cryopyrin in NF-kappa-B and pro- caspase-1 activation. It suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes and inhibits NF-kappa-B activation by cytokines and LPS.

WDR82

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 83%; Dog: 83%; Goat: 83%; Guinea Pig: 85%; Horse: 83%; Human: 100%; Yeast: 77%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

9kDa

Wet Ice

89

PYDC1

PYDC1

Rabbit

Pyrin domain-containing protein 1

REAILKVLENLTPEELKKFKMKLGTVPLREGFERIPRGALGQLDIVDLTD