RACGAP1 Antilichaam - N-terminal regio : HRP (ARP31905_T100-HRP)

Rac GTPase activating protein 1

CYK4, ID-GAP, HsCYK-4, MgcRacGAP

29127

Q9H0H5

NP_037409

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the N terminal region of human RACGAP1

Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO, RAC, and CDC42. GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.

MORF4L1; UBC; FZR1; MPG; TXNDC11; MPRIP; TANK; KIF23; AURKB; PPP2R4; ECT2; CDK1; IKBKG; CUL1; SH3KBP1; Racgap1; Shcbp1; Cd2ap; YWHAG; YWHAB; PRC1; SH3RF1; SLC26A8; SLC16A10; PRSS23; CHN2; MAP3K4; RND2; MAP3K10; TUBG1; TUBA4A; VAV1; NRAS; GRB2; SFN

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 100%; Rat: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

71kDa

Niiya, F., et al., (2005) J. Biol. Chem. 280 (43), 36502-36509

Wet Ice

632

RACGAP1

RACGAP1

Rabbit

Rac GTPase-activating protein 1

NM_013277

EILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMKAETERSALD