Raf1 (Ab 338) Antilichaam

Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. Part of the Ras-dependent signaling pathway from receptors to the nucleus. Protects cells from apoptosis mediated by STK3.

5894

P04049

NP_002871.1

Human, Mouse

Raf1 (Ab-338) antibody was raised against a peptide sequence around aa.336~340 (R-D-S-S-Y) derived from Human RAF.

Unconjugated

Primary Antibodies

Apoptosis, Cancer

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

None

Blue Ice

Store antibody at -20˚ C for up to one year.

73 kDa

This antibody detects endogenous level of total Raf1 protein.

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

RAF1

V-raf-1 murine leukemia viral oncogene homolog 1

Homo sapiens

Adams DG, et al. (2005) J Biol Chem. 280 (52) : 42644-54. Miura S, et al. (2003) Biochem Biophys Res Commun. 306 (4) : 924-9. Noser JA, et al. (2007) Mol Ther. 15 (8) : 1531-6.

NS5, CRAF, Raf-1, c-Raf, ESR, NR3A1, C-RAF, C-Raf

WB, IHC

4506401

Liquid