RALBP1 Antilichaam - N-terminalgebied: HRP (ARP52251_P050-HRP)

RalA binding protein 1

RIP1, RLIP1, RLIP76

10928

Q15311

NP_006779

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Pig, Rabbit

The immunogen is a synthetic peptide directed towards the N terminal region of human RALBP1

RALBP1 can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. RALBP1 mediates ATP-dependent transport of S- (2,4-dinitrophenyl) -glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes.RALBP1 can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. RALBP1 serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin.

TNIP1; CEP57; SMARCE1; PPL; GPS2; GSE1; ZNF707; ZBTB38; C1orf216; TBRG1; AMOTL2; TFPT; UBC; RALB; GPSM1; PRKCA; CPSF2; POLR2A; AP2A1; SYNJ2BP; HOOK2; REPS1; FADD; RAC1; TRAF2; CASP8; AP2M1; REPS2; IKBKG; RALA; CCNB1; HSP90AA1; HSF1; EPN1; NUMB; GTF3A; TNF

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB, IHC

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Goat: 86%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

76kDa

Wet Ice

655

RALBP1

RALBP1

Rabbit

RalA-binding protein 1

NM_006788

MTECFLPPTSSPSEHRRVEHGSGLTRTPSSEEISPTKFPGLYRTGEPSPP