RASSF1 Antilichaam - C-terminalgebied: HRP (ARP59681 P050-HRP)

Ras association (RalGDS/AF-6) domain family member 1

123F2, RDA32, NORE2A, RASSF1A, REH3P21

11186

Q9NS23

NP_733831

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep, Zebrafish

The immunogen is a synthetic peptide directed towards the C terminal region of human RASSF1

This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Seven alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

FBXW11; MDM2; DAXX; SUV39H2; KDM1A; SUV39H1; STK4; STK3; CDC20; SAV1; MAST2; HUWE1; LATS1; BTRC; UBC; ID1; GSK3B; C7orf25; C8orf33; KCNE3; CUL4A; DDB1; Rassf1; SKP2; AURKB; AURKA; SKP1; CUL1; NUDT10; MOAP1; CNKSR1; MAP1S; EXOSC8; RASSF5; TNFRSF10A; E4F1

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 93%; Rat: 100%; Sheep: 100%; Zebrafish: 85%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

30kDa

Wet Ice

270

RASSF1

RASSF1

Rabbit

Ras association domain-containing protein 1

NM_170713

LAGPSDKALSFVLKENDSGEVNWDAFSMPELHNFLRILQREEEEHLRQIL