RB1CC1 Antilichaam - C-terminaal gebied: Biotine (ARP50467_P050-Biotine)

RB1-inducible coiled-coil 1

CC1, ATG17, FIP200, PPP1R131

9821

Q8TDY2

NP_001077086

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish

The immunogen is a synthetic peptide directed towards the C terminal region of human RB1CC1

RB1CC1 is implicated in the regulation of RB1 expression. It functions as a DNA-binding transcription factor. RB1CC1 is a potent regulator of the RB1 pathway and a mediator that plays a crucial role in muscular differentiation. The expression of RB1CC1 is, thus, a prerequisite for myogenic differentiation. RB1CC1 is frequently mutated in breast cancer and shows characteristics of a classical tumor suppressor gene.

ATG16L1; SESN2; ATG5; UBC; EXOC1; DYRK2; PINK1; CALCOCO2; RFWD2; CTNNB1; GABARAPL1; GABARAP; VHL; RNF111; SMARCB1; SKIL; SKI; TBKBP1; TP53; ATG13; ULK2; SAFB2; ULK1; SAFB; RPA2; RPA1; PRKAB2; PRKAA2; HSBP1; MAP1LC3C; SMCR8; ATG101; YLPM1; TBK1; RBMX; PTK2

Biotin

Polyclonal Antibody

WB, IHC

Affinity Purified

RB1CC1 is strongly supported by BioGPS gene expression data to be expressed in HEK293T

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

183kDa

Hara, T., (2008) J. Cell Biol. 181 (3), 497-510

Wet Ice

1591

RB1CC1

RB1CC1

Rabbit

RB1-inducible coiled-coil protein 1

NM_001083617

SGASRRPWVLGKVMEKEYCQAKKAQNRFKVPLGTKFYRVKAVSWNKKV