Recombinant humaan/muur/rat BDNF-eiwit

Molecular Weight: 13 KDa Description: Recombinant Human Brain-Derived Neurotrophic Factor is produced by our E.coli and the target gene encoding His129-Arg247 is expressed. Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. It also binds with the LNGFR (for low-affinity nerve growth factor receptor, also known as p75) . BDNF promotes the survival, growth and differentiation of neurons. It serves as a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. BDNF expression is altered in neurodegenerative disorders such as Parkinson's and Alzheimer's disease.

Brain-Derived Neurotrophic Factor; BDNF; Abrineurin

P23560

BDNF

Lyophilized from a 0.2 ?m filtered solution of 20mM PB, 250mM NaCl, pH 7.2.

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.