Resibufogenine
Gecertificeerd

Resibufogenine

Catalog #: C09229-01
Maat: 1 mg

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%
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Gratis verzending vanaf €100

Technische Specificaties

CAS Number

465-39-4

Synonyms

Bufogenin, Recibufogenin

SKU

C09229-5mg

Target

RIP kinase

Applications

Apoptosis

Smiles

CC12CCC (O) CC1CCC3C2CCC4 (C) C (CC5OC345) C6=COC (=O) C=C6

Molecular Formula

C24H32O4

Additionnal Information

Resibufogenin (Bufogenin, Recibufogenin), a component of huachansu with anticancer effect, triggers necroptosis through upregulating receptor-interacting protein kinase 3 (RIP3) and phosphorylating mixed lineage kinase domain-like protein at Ser358. Resibufogenin exerts cytotoxic effect by inducing reactive oxygen species (ROS) accumulation. Resibufogenin induces apoptosis and caspase-3 and caspase-8 activity. Resibufogenin increases Bax/Bcl-2 expression, and suppresses cyclin D1, cyclin E, PI3K, p-AKT, p-GSK3β and β-catenin protein expression.

Storage Conditions

3 years -20°C powder

Beschrijving

Resibufogenine Beschikbaar in 1 mg. Bestel eenvoudig online met snelle levering.

Specificaties

ProductnaamResibufogenine
Categorie
Beschikbare grootte1 mg
CatalogusnummerC09229-01