Rhodamine 123

Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms[1].

62669-70-9

RH-123; R-22420

12171500

H302

Fluorescent Dye

Dye Reagents

Others

COVID-19-immunoregulation

Cardiovascular Disease

https://www.medchemexpress.com/Rhodamine_123.html

10mM

99.73

DMSO : 41.67 mg/mL (ultrasonic)

O=C(C1=CC=CC=C1C2=C3C=CC(N)=CC3=[O+]C4=C2C=CC(N)=C4)OC.[Cl-]

C21H17ClN2O3

380.82

H302

[1]M. Huang, et al. Mitochondrial Inner Membrane Electrophysiology Assessed by Rhodamine-123 Transport and Fluorescence. Ann Biomed Eng. 2007 Jul; 35 (7) : 1276–1285.|[2]Emaus, R. K., Grunwald, R., & Lemasters, J. J. (1986) . Rhodamine 123 as a probe of transmembrane potential in isolated rat-liver mitochondria: spectral and metabolic properties. Biochimica et Biophysica Acta (BBA) - Bioenergetics, 850 (3), 436–448.

Room Temperature

4°C (Powder, sealed storage, away from moisture and light)

http://file.medchemexpress.com/batch_PDF/HY-D0816/Rhodamine-123-SDS-MedChemExpress.pdf

Dye Reagents

No Development Reported