Rigosertib (ON-01910)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
1225497-78-8
C16269-10mg
PLK
Cell Cycle
COC1=C (C=C (C=C1) CS (=O) (=O) C=CC2=C (C=C (C=C2OC) OC) OC) NCC (=O) [O-].[Na+]
C21H24NNaO8S
Rigosertib (ON-01910) is a non-ATP-competitive inhibitor of PLK1 with IC50 of 9 nM in a cell-free assay. It shows 30-fold greater selectivity against Plk2 and no activity to Plk3. Rigosertib inhibits PI3K/Akt pathway and activates oxidative stress signals. Rigosertib induces apoptosis in various cancer cells. Phase 3.
2 years -80 in solvent
Beschrijving
Rigosertib (ON-01910) Beschikbaar in 10 mg. Wordt geleverd met droogijs. Bestel eenvoudig online met snelle levering.
Specificaties
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