
Ripretinib
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
1442472-39-0
DCC-2618
C13645-5mg
C-Kit
Protein Tyrosine Kinase
CCN1C2=CC (=NC=C2C=C (C1=O) C3=CC (=C (C=C3Br) F) NC (=O) NC4=CC=CC=C4) NC
C24H21BrFN5O2
Ripretinib is an orally bioavailable switch pocket control inhibitor of wild-type and mutated forms of the tumor-associated antigens (TAA) mast/stem cell factor receptor (SCFR) Kit (c-Kit) and PDGFR-alpha, with IC50 values of 4 nM, 8 nM, 18 nM, 5 nM and 14 nM for WT Kit (c-Kit), V654A Kit (c-Kit), T670I Kit (c-Kit), D816H Kit (c-Kit) and D816V Kit (c-Kit), respectively.
3 years -20°C powder
Beschrijving
Ripretinib Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
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