SARS-CoV-2 (COVID-19) Spike Q493R G496S Q498R N501Y Y505H Antilichaam (Omicron)

SARS-CoV-2 Omicron variant, a variant of concern (VOC), known as B.1.1.529, was detected in South Africa at the end of November in 2021. However, it rapidly spread all over of the world and now it is the dominant variant in the world, which account for more than 90% of the new cases. Omicron variant spike protein carries around 30 amino acid changes, including mutations, deletions and insertions, in which the receptor binding domain (RBD) protein contains 15 mutations. Enhanced transmission of the Omicron variant was observed globally, which is at least 70 times more contagious than the other variants. The Omicron variant affects the effectiveness of COVID-19 vaccine and is resistant to neutralization (monoclonal antibody treatments) to a large extent

43740568

P0DTC2

QHD43416

Virus

9805

Unconjugated

Primary Antibodies

Infectious Disease, COVID-19

Anti-SARS-CoV-2 Omicron Variant Spike antibody is affinity chromatography purified via peptide column.

1 mg/mL

Predicted reactivity based on immunogen sequence: SARS-CoV Spike proteins: (55%)

Anti-SARS-CoV-2 Omicron Variant Spike antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

SARS-CoV-2 Omicron Variant Spike antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

It can only detect SARS-CoV-2 Omicron Variant (B.1.1.529) Spike protein and does not cross-react with the spike proteins of other variants.

S

Surface glycoprotein

Severe acute respiratory syndrome coronavirus 2

Gowrisankar et al. European Physical Journal Plus, 2022, 137 (1), 100.

Zhang et al. PNAS of U.S.A. 2021, 118 (47) :e2109905118.

Cameroni et al. Nature 2021.

Rossler et al. NEJM 2022.

Muik et al. Science 2022.

SARS-CoV-2 Omicron Variant Spike antibody: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Surface Glycoprotein, Spike protein, Omicron Variant

ELISA, WB, IF, Neutralization Assay

1791269090

Liquid