SCO-L-Lysine

SCO-L-Lysine contains a SCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups. SCO-L-Lysine can be incorporated into the protein of interest by the tRNAPyl/PylRSAF synthetase[1].

1309581-49-4

12352211

Biochemical Assay Reagents

Reference compound

Others

Others

https://www.medchemexpress.com/sco-l-lysine.html

10 mM in DMSO

N[C@H](C(O)=O)CCCCNC(OC1C#CCCCCC1)=O

C15H24N2O4

296.36

[1]Anandi Kugele, et al. In situ EPR spectroscopy of a bacterial membrane transporter using an expanded genetic code. Chem Commun (Camb) . 2021 Dec 3;57 (96) :12980-12983.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-157070/

Reference compound1

No Development Reported